Search by name
logo

Guillain-Barré Syndrome

Guillain-Barré Syndrome is a rare disorder in which the body’s immune system attacks nerves. Tingling and weakness in hands and feet are some of first symptoms of the condition. These sensations eventually spread throughout the body causing paralysis.

The primary cause of Guillain-Barré Syndrome is unknown. However, two-thirds of people with Guillain-Barré Syndrome reported infection like symptoms six weeks before being diagnosed with Guillain-Barré Syndrome. This can be gastrointestinal infection, respiratory infection, or Zika virus.

Symptoms

Generally, the symptoms begin with tingling that starts from the hands and body and then proceeds to the arms and face and then throughout the body. As this condition progresses, Guillain-Barré Syndrome can lead to paralysis.

Some other symptoms of Guillain-Barré Syndrome are as follows:

  • Rapid heart rate
  • A needle and pin-like sensation in toes, wrists, fingers, or ankles
  • Weakness in the legs that spreads to your body
  • Inability to walk or climb stairs
  • Inability to move the eyes
  • Difficulty with facial movements, like chewing, speaking, or swallowing
  • Chronic pain that feels like a shooting pain, cramping or aching and gets worse at night
  • Difficulty breathing
  • Rapid heart rate
  • Difficulty with bowel function or bladder control

Causes

Though the main cause is unknown, research indicates the following can be triggers of Guillain-Barré Syndrome.

  • Respiratory illness or diarrhoea – Many patients later diagnosed with Guillain-Barré Syndrome had diarrhoea or respiratory illness a few weeks before developing its symptoms.
  • Viral infections – Some people also had infections or flu with the Zika virus, Epstein-Barr virus, or others.
  • Vaccination – Few people also develop this problem after getting certain vaccinations. However, the benefits of vaccinations outweigh Guillain-Barré Syndrome risks.

Risk Factors

Experts suggest that the most common risk factor is Campylobacter jejuni infection, which is a bacteria that cause diarrhoea. It’s usually found in undercooked meat, like poultry. Here are a few more infections linked to Guillain-Barré Syndrome.

  • Epstein-Barr Virus (EBV)
  • AIDS or HIV
  • Mononucleosis
  • Cytomegalovirus (CMV)
  • Mycoplasma Pneumonia

Diagnosis & Complications

The diagnosing process typically starts with a full medical history and physical examination.  Guillain-Barré Syndrome can be difficult to diagnose, especially in the early stages, your doctor is likely to recommend additional tests including:

Spinal tap (lumbar puncture) -when fluid is withdrawn from the spinal canal in your lower back and is test for changes associated with Guillain-Barre syndrome.

Electromyography- Small needle like electrodes are inserted into the muscles in your body that the doctor wants to study to measure the nerve activity within these muscles.

Nerve conduction studies –this test measures the speed of nerve signals by placing electrodes on the skin above the nerves then sends a small shock to the nerve.

Treatment & Prevention

Most health experts believe plasmapheresis is the best treatment if you are diagnosed with Guillain-Barré syndrome. In this process, they will take blood from your body, clean it, and return it to your body. Your health provider will also give you antibodies or immunoglobulin along with a high dose of healthy cells through an IV. These treatment methods can help reduce the immune system’s attack on your body.

Scientists and doctors have not yet determined how to prevent Guillain-Barré syndrome. This syndrome is a serious condition that can deteriorate rapidly and requires immediate hospitalization. The quicker  treatment is started, the better the chance of a good outcome.

 
 
 

The content appearing on this site is not intended to treat, diagnose, or provide health care advice. The articles you read here are meant for informational purposes only. Please review additional information to learn more.