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Brain Tumours

Brain tumours are growths of abnormal cells in or near the brain. Brain tumours occur not only in the brain itself, but in nearby tissues. Brain tumours can be cancerous (malignant) or non-cancerous (benign). Depending on where the tumour is located in the brain and if the tumour is cancerous, the tumour may be noticed early on or it may take a long time for someone with a brain tumour to notice any symptoms at all.

There are several types of brain tumours. Each is defined by the cell type that makes up the tumour. The most common brain tumours include:

  • Gliomas – gliomas are usually cancerous and are made up of a type of nerve cell called glial cells. Glial cells and their related cells, like oligodendrocytes and astrocytes, act as support cells for neurons, the cells that operate the brain.
  • Germ cell tumours – These tumours start in reproductive cells, also known as germ cells, that usually go on to become sperm and eggs. However, there are a few germ cells near the pituitary gland and the pineal gland. Mostly benign, germ cell tumours usually occur in children.
  • Nerve tumours – these tumours occur in and around the nerves.
  • Pineal tumours – Begin in and near the pineal gland. The pineal gland helps regulate sleep by releasing the hormone melatonin, and tumours here can be benign or malignant.
  • Embryonal tumours – These tumours occur in young children and are usually malignant. After birth, a small amount of embryonic cells, or cells from a child’s foetal development, remain in the brain. This is where embryonal tumours begin.
  • Pituitary tumours – the pituitary gland is a tiny structure right under the brain that is known as the “master gland”. It helps control bodily functions in almost every organ system. Pituitary tumours begin in the gland and are usually non-cancerous.
  • Choroid plexus tumours – these tumours form in the fluid that encases the brain, known as cerebrospinal fluid.

Symptoms

Common symptoms of brain tumours include:

  • Trouble making decisions and/or irrational decision making
  • Difficulty making coordinated movements
  • Balance issues
  • Difficulty walking
  • Personality changes
  • Speech issues
  • Vision issues like double vision and blurred vision
  • Hearing loss
  • Sensory problems
  • Memory issues
  • Detection of a sight, taste, or smell that is not really there
  • Headaches
  • Nausea and vomiting
  • Fatigue
  • Confusion
  • Seizures
  • Hunger and weight gain
  • Trouble sleeping
  • Numbness in the arms and legs

Causes & Risk Factors

Brain tumours are caused by a change, or mutation, in a gene that tells the cells it lives in to start growing quickly and reproducing as fast as possible, leading to an abnormal mass of cells. Some gene changes that cause brain cancer are inherited, but these are rare cases. Most of the time, the cause of the gene change is unknown.

Risk factors include:

  • Age – Certain brain tumours are more likely to happen in the elderly, whereas other brain tumours are more likely to happen in children.
  • Radiation exposure.
  • Inherited syndromes that increase the likelihood of brain tumour development.

Diagnosis & Complications

Based on a thorough neurological exam and your medical history, your doctor may order further testing if they suspect a brain tumour. Tests for a brain tumour include imaging like a computerised tomography scan (CT) or a magnetic resonance imaging scan (MRI) that will allow your doctor to see any type of abnormal cell growth in or near your brain. They may also want to take a small sample of the tumour tissue for testing.

Complications include:

  • Seizure disorder
  • Cognitive and learning disabilities
  • Depression
  • Long-term memory issues
  • Trouble communicating effectively

Treatment & Management

Treatment will depend on the size, location, and speed of growth of the tumour. It also depends on the current health of the patient and their wishes. Options include surgery, radiation therapy, chemotherapy, and targeted drug therapy. It’s also possible that immediate treatment is not necessary, and that the tumour will need to be monitored over time.

 
 
 

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