Search by name
logo

Urothelial Carcinoma (Bladder Cancer)

Urothelial carcinoma is a common form of bladder cancer that begins in the cells that make up the lining of the bladder, urethra, and ureters, which are thin tubes that connect the kidneys to the bladder.  The outlook for urothelial carcinoma is often good when caught early, but this form of cancer has a tendency to recur.

What Causes Bladder Cancer?

It must be noted that cancer can happen to anyone, regardless of lifestyle and family history. However, there are some risk factors that increase your chances of developing urothelial carcinoma:

  • Smoking Cigarettes – Cigarettes are a risk factor for many types of cancer, including urothelial carcinoma. 
  • Being Exposed to Chemicals – Exposure to chemicals like arsenic also increases your bladder cancer risk, especially when exposure occurs on a regular basis (such as when working at a manufacturing plant).

Chronic bouts of bladder inflammation can also increase one’s risk, as can undergoing previous bladder cancer treatment and being over the age of 65.

Reference Articles

Symptoms

People with this form of bladder cancer often experience the following symptoms:

  • Discoloured or bloody urine
  • Painful urination
  • Fatigue
  • Frequent back pain

Some people also detect the sensation of a lump or swelling in their back in the location of the kidney. These symptoms should be assessed by a doctor, who can perform a physical exam and diagnostic tests to help you find an accurate diagnosis.

How Urothelial Carcinoma Is Treated

Treatment of bladder cancer depends on factors like the severity of symptoms, your general state of health, and whether the cancer has spread. Once your doctor performs a comprehensive evaluation, they will usually recommend one or more of the following treatments:

  • Surgery

Surgery can be used to remove cancerous tumours. In the event urothelial carcinoma spreads to the kidneys, doctors can remove all or a portion of the affected organ.

  • Radiation Therapy

Radiation therapy uses targeted energy to eliminate the presence of cancerous cells within the body.

  • Immunotherapy

This treatment uses medications that enhance a person’s immune system to better fight off cancerous cells.

  • Chemotherapy (Intravesical vs. Systemic)

Intravesical chemotherapy is used to treat bladder cancer when it is limited to the lining of the bladder cells. Conversely, whole body or systemic chemotherapy delivers medication to the entire body and is often recommended when surgery is not viable.

Doctors may also recommend target drug therapy, which is often combined with chemotherapy. Targeted drug therapy involves using medications designed to attack cancerous cells specifically.

 

 
 
 

The content appearing on this site is not intended to treat, diagnose, or provide health care advice. The articles you read here are meant for informational purposes only. Please review additional information to learn more.