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HIV-2

Human Immunodeficiency Virus -HIV-2 is a type of retrovirus. It is one of the root causes of AIDS. Like HIV-1, HIV-2 infects immune cells that affect or reduce the body’s natural ability to prevent diseases and infection.

HIV-2 is primarily found in West Africa and is less common than HIV-1, which is found worldwide. The transmission and progression of HIV-2 are similar to that of HIV-1, but this virus tends to progress more slowly to AIDS.

Symptoms

Most HIV-2 symptoms are similar to HIV-1. However, some symptoms can take longer to appear or be less serious, depending on the condition. People with HIV-2 often do not experience symptoms for several years after infection.

The signs of early HIV-2 infection may look like this:

  • Flu-like symptoms: weakness, high temperature, headache, joint and muscle aches, and sore throat.
  • Rash: A rash may appear on the trunk, face, or arms.
  • Swollen glands: Swollen lymph nodes, especially in the neck, armpits, and groin.
  • Mouth sores: Small, painful sores may develop in the mouth.

As HIV-2 leads to AIDs that can cause more severe symptoms such as:

  • Opportunistic Infections: Damaged immune system that makes the patient more prone to catch viral and bacterial infections.
  • Weight loss: Significant weight loss.
  • Persistent diarrhoea: weak digestion.
  • Fatigue: weakness followed by tiredness can become more severe and persistent.
  • Cognitive difficulties: Memory loss, confusion, and other cognitive difficulties can occur as the virus attacks the brain.

Causes

The Human Immunodeficiency Virus type-2 causes HIV-2 in people. HIV-2 attacks the immune system, specifically the CD4 cells, which play a critical role in fighting infections. Once the virus infects these cells, it injects its genetic material into the cell’s DNA and reproduces itself. When it happens, the health of the person starts worsening.

Risk Factors

These are the factors that may increase the risk of contracting HIV-2.

  • Sexual Contact: Having unprotected sex with an infected person increases the risk of HIV-2 transmission. This may include anal, vaginal, and oral sex.
  • Sharing Needles: Sharing needles or injection tools with HIV-2 infected persons can also lead to virus transmission.
  • Mother-to-child transmission: Pregnant women with HIV-2 can pass the virus to their babies during pregnancy, childbirth, or breastfeeding.
  • Blood Transfusions: In some countries, blood transfusions may still pose a risk of contracting HIV-2, although this is becoming increasingly rare with improved blood testing methods.
  • High-risk Sexual Behaviour: Having unprotected sex with multiple sexual partners and having a history of STIs (sexually transmitted diseases) can increase the risk of contracting HIV-2.
  • Substance Abuse: Substance abuse, especially drug use through injections can increase the risk of contracting HIV-2 through shared needles and other injection equipment.

Diagnosis or Complications

Typically, a blood test is done to detect the presence of HIV-2 (antibodies). If the initial test is positive, a doctor does a confirmatory test to confirm the diagnosis. It’s crucial to get tested if there is any chance you have been exposed to the virus. Early diagnosis is critical for starting treatment and managing the virus effectively.

If not detected on time, the virus develops and attacks your body’s defence mechanism, leading to health complications like;

  • Cardiovascular Disease: People with HIV-2 are at increased risk for heart disease, stroke, and other cardiovascular complications.
  • Neurocognitive Complications: HIV-2 attacks the brain, causing memory and other cognitive difficulties.
  • AIDS: When not treated timely, HIV-2 progresses to AIDS. It is an advanced stage of the virus. AIDS patients may have severely weak immunity and are at increased risk for serious infections.

Treatment & Prevention

Like HIV-1, doctors use antiretroviral therapy (ART) to treat the virus initially. It slows down the damage virus has caused to the immune system.

ART aims to achieve and maintain an undetectable virus in the blood. This improves health and lessens the risk of transmitting the virus to others.

To prevent HIV-2, medical professionals recommend;

  • Safe sex practices
  • Using sealed needles and injection equipment
  • Early STIs testing
  • Antiretroviral therapy for pregnant mothers

Understanding the factors that can increase the risk of HIV-2 and getting tested as soon as possible can help you prevent the infection.

 
 
 

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