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Hepatic Jaundice

Hepatic jaundice takes place when the liver tissue is scarred, has been damaged, or becomes dysfunctional. This makes the liver less effective at filtering bilirubin from the blood. Bilirubin can then build up in the blood to dangerously high levels. This condition can be caused by a variety of different health issues or lifestyle choices and requires immediate supportive care in order to manage the progression of the condition.

Symptoms

The common symptoms of hepatic jaundice are:

  • Loss of appetite
  • Bloody noses
  • Skin itching
  • Weakness
  • Abnormal weight loss
  • Swelling in the abdomen or the legs
  • Dark urine or pale stools
  • Pain in the muscles and the joints
  • Darkening of the skin
  • Fever
  • Feeling sick
  • Vomiting
  • Yellowing of the whites of the eyes

Causes & Risk Factors

The most common causes of hepatic jaundice are:

  • Liver cirrhosis that has been caused by exposure to toxic substances or excessive amounts of alcohol.
  • Viral hepatitis, which is an inflammation that can be caused by viruses that can enter the body via infected food, water, blood, stool, or sexual contact.
  • Primary biliary cirrhosis which is caused by damaged bile ducts that cannot process bile correctly.
  • Alcoholic hepatitis, which happens when long-term heavy drinking leads to scarring of the liver tissue.
  • Liver cancer.
  • Leptospirosis which is a bacterial infection that can be spread by humans or animals via infected faeces or urine.

The common risk factors for this condition are:

  • Drug use
  • Drinking lots of alcohol over an extended period of time
  • Use of medications that can impact the health of the liver, such as NSAIDs
  • Previous infections that have affected the health of the liver

Diagnosis

Diagnosis of this condition is made through the use of a variety of tests. Your doctor will likely order a urinalysis and blood tests like a CBC to check on the bilirubin levels in your blood and to look for substances that are not being filtered out of your system correctly by the liver.

You might also need to have imaging tests done like MRI or ultrasound to check the health of your liver and look for growths and tumours on the liver. An endoscopy can also be done to collect a small biopsy of tissue from the liver for examination. A biopsy is most commonly done when checking for cancer of the liver.

Treatment & Prevention

The treatment of this kind of jaundice requires figuring out the root cause. The condition that is causing jaundice will then need to be treated in order to provide relief for the jaundice itself. In the case of those who have cirrhosis from drinking or drug use, getting clean will be a big factor in treating the cirrhosis associated with substance abuse.

Treatment of liver cirrhosis usually involves the use of beta blockers to help with blood circulation, and changes to diet might be needed to help the liver function more effectively. IV antibiotics might be given to those with liver infections. If a person’s cirrhosis has been caused by a virus, antivirals might be prescribed to help shorten the duration of the illness.

Liver cirrhosis typically cannot be healed entirely, but patients can be given digestive aids that they can take on a daily basis to help with digestion. They might also be given medications that lower the bile in the system and help the liver filter bilirubin more effectively. In severe cases, a liver transplant might be a patient’s best or only option.

Prevention of this condition might not always be possible. However, for those who drink too much alcohol or use drugs on a regular basis, avoiding these substances can be the best way to prevent hepatic jaundice. There are also hepatitis vaccinations that can be given to help prevent illness if there is a chance that you could be exposed to viral hepatitis. Treatment of underlying conditions that can impact liver health is also a key preventative that is necessary to keep hepatic jaundice at bay.

 
 
 

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