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What Causes Seizures?

A seizure is a condition in which the brain cells malfunction and send excess electrical signals to certain parts of the organ. Depending on the part of the brain affected, episodes can range in terms of severity, duration and symptoms. It is important to note that any person can have a seizure, and for a variety of reasons. However, some people are more susceptible to them than others. It is also important to note that seizures can be easily treated. However, effective treatment depends almost exclusively on first identifying the underlying cause.

Why Do Seizures Occur?

In the most basic sense, seizures occur because the brain experiences an uncontrollable surge of electrical activity. When this happens, the brain cells that are affected fire signals uncontrollably to surrounding cells, thereby resulting activity overload within the brain. Depending on the areas affected, this overload can result in a myriad of symptoms, including but not limited to uncontrollable muscle movements, abnormal sensations and unconsciousness. Effective treatment depends largely on the underlying cause and type of seizure a person experiences.

How Common Are Seizures?

South Africa has a high prevalence rate of seizures or, more particularly, of epilepsy — meaning unprovoked seizures. Provoked seizures are seizures that occur because of an external trigger, such as heavy alcohol use, low blood sugar and high fevers. Unprovoked seizures, however, are those that occur spontaneously and with no discernible cause. Healthcare providers typically diagnose someone with epilepsy after two unprovoked seizures occur.

In South Africa, epilepsy affects approximately 1 in 100 people, which means it affects approximately half a million South Africans. The country has one of the highest incidence rates of epilepsy of any other country in the world. If every person who lives with epilepsy has at least four immediate family members, the country anticipates that another 2 million people are affected by the condition but do not know it yet.

Who Do Seizures Usually Affect?

Most people are likely to experience their first seizure by the age of 20. However, they are most common in people of certain ages. For example, seizures and epilepsy are more likely to affect young children who eventually outgrow the condition by the time they are adults. On the other hand, the risk of having seizures increases after the age of 50, oftentimes due to stroke.

Causes of Seizures

If you or a loved one experience seizures and/or have been diagnosed with epilepsy, you may be seeking answers. Why do these seizures occur, and what can you do about them? For the most effective treatment, it is first important to identify the underlying causes of the episodes. Below are a few of the top causes of seizures:

  • Drug or alcohol use (this includes both recreational drugs and prescription medications)
  • Withdrawal from drugs or alcohol
  • Excessive coffee consumption
  • Brain tumours
  • Aneurysms
  • Degenerative brain diseases, such as Alzheimer’s disease
  • Traumatic brain injury or severe concussion
  • Lack of oxygen to the brain (cerebral hypoxia)
  • Electrolyte imbalances, such as due to low sodium, magnesium or calcium
  • High fevers
  • Eclampsia, which is a condition that affects pregnant women and causes their blood pressure to spike
  • Genetic disorders
  • Sensitivity to flickering or flashing lights
  • Infections, such as meningitis and encephalitis
  • Hormone-related changes, such as those related to the menstrual cycle
  • Metabolic issues, such as high or low blood pressure
  • Autoimmune-disorder related inflammation
  • Issues with the brain structure
  • Mental health disorders
  • Sepsis
  • Stroke
  • Exposure to poisons or toxins, such as heavy metal or carbon monoxide poisoning

Warning Signs of a Seizure

Though seizures are often portrayed as “sudden events,” the truth is that many people can sense “signs” before an episode occurs. Individuals who have reoccurring seizures typically recognize these signs and know to take precautions before the actual onset of the episode. The signs are also so well-known by healthcare professionals that there is an actual term for the pre-seizure symptoms: prodrome, which some people refer to as an “aura.”

The aura is associated with just a focal seizure (or seizure of one side of the brain) and, for some people, is the only symptom they will experience. If the focal seizure spreads, however, the aura often serves as a warning sign that a seizure is about to occur and that the afflicted person should seek safe surroundings. Auras may take several forms, the most common of which are as follows:

  • Emotional Changes: One characteristic of an aura is emotional changes. Auras often make sufferers feel negative emotions, including fear and anxiety, though some people experience positive emotional changes, such as excitement or joy. Some afflicted persons claim to experience de ja vu leading up to a focal seizure.
  • Sensory Issues: Sensory symptoms are also common of auras. When an aura begins, some people may see objects as distorted or bright lights that are not actually there. They may also hear unexpected sounds, taste or smell strange things, or feel strange sensations along their skin. This is often due the fact that some seizures affect areas of the brain connected to the neurons, thereby causing them to believe they are getting real input.
  • Autonomic Symptoms: Some auras affect the symptoms of the brain that operate automatically. For instance, some sufferers may sweat profusely, drool uncontrollably, or blush or go pail for no reason. It is also not uncommon for people to experience “gastric uprising,” or a rising feeling in the stomach, preceding a seizure.

Seizure Complications

Seizures, if they occur infrequently and in a safe place, generally do not have any lasting complications. However, if they occur when you are engaged in an activity, in a precarious situation or frequently, they may have serious complications for your health and well-being. Some common complications of seizures are as follows:

  • Drowning: When seizures occur while you are swimming or bathing, there is the very real risk that you may drown if someone is not there to keep your head above water.
  • Falling: If you fall during a seizure, you are at risk of breaking a bone or causing a head injury.
  • Car Accidents: If a seizure occurs while you are driving, you could lose loss of consciousness or awareness and, therefore, cause a car accident.
  • Emotional Health Issues: People who live with seizure disorders are more likely than others to develop emotional health issues, such as anxiety and depression.
  • Pregnancy Complications: When seizures affect pregnant women, mom and baby may be at risk for health complications. Though seizures can be controlled with medications, many anti-seizure medications increase the risk of birth defects.

Risk of Sudden Death

It is important to note that epilepsy does come with a small risk of sudden expected death in epilepsy (SUDEP). Doctors are unclear of why SUDEP happens, though they suspect it has to do with breathing problems or changes in heart rhythm. For people with managed epilepsy — meaning, they are seeking treatment for it — the death rate per year is approximately 1 out of every 1,000 persons. For people who live with unmanaged epilepsy, the death rate is significantly higher, at 1 per 150 persons.

Medical Conditions

The Bottom Line

Seizures can be scary, both for individuals who experience them and their loved ones. That said, they are often manageable once you and a doctor determine an underlying cause. For this reason, it is so important to seek a diagnosis as soon after you experience your first seizure as possible. The sooner you do, the less likely you are to experience dangerous seizure complications.

 
 
 

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