Sometimes referred to as progressive facial hemiatrophy, Parry-Romberg syndrome (PRS) causes facial tissue to break down over time. The condition often affects one side of the face, but in rare instances both sides can undergo tissue loss. PRS is also associated with other health effects, such as seizures.
Doctors aren’t entirely sure what causes PRS, but it’s often linked to the following health conditions:
Symptoms of PRS first present in childhood. The condition is more common in female children, but it can affect male children as well.
The effects of PRS can range from mild to severe, which impacts treatment options. When the effects are severe and associated with neurological symptoms, doctors can recommend surgery. These procedures aren’t usually performed until the condition stops advancing.
When an autoimmune condition is present in people with PRS, doctors may also prescribe immunosuppressant therapy. Certain autoimmune conditions can cause the immune system to overreact to facial inflammation, which can then lead to symptoms like:
It is worth noting that researchers are still evaluating whether immunosuppressant medication is best for people with PRS. A doctor can help parents determine the best possible treatment for their children based on the specific effects of the condition.