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Cryptococcus Gattii Infection

Cryptococcosis is an infection caused by Cryptococcus gattii fungus, which thrives in soil and on trees. Inhalation of these fungal spores can lead to symptoms like shortness of breath, cough, chest pain, fever, and other health effects.

Not everyone who’s exposed to Cryptococcus gattii fungus experiences symptoms. When symptoms do occur, doctors typically use one of the following antifungal medications depending on the severity of the patient’s health effects.

Fluconazole

When the symptoms associated with cryptococcosis are mild and confined to the lungs, doctors will most likely prescribe an antifungal medication known as fluconazole. This medication is usually taken in tablet form, but a powder version is also available.

Fluconazole is associated with some side effects, including:

  • Skin rash
  • Headache
  • Nausea
  • Diarrhoea
  • Stomach pain

Patients are encouraged to talk with their doctor if they experience persistent side effects. More serious side effects, such as an irregular heartbeat, require immediate medical attention.

Amphotericin B and Flucytosine

Cryptococcosis can sometimes cause effects outside of the lungs and impact the central nervous system. In this case, or when fungal lung infections are classed as severe, patients will receive medications called amphotericin B and flucytosine. Amphotericin B is an injectable antifungal medication, while flucytosine is an oral antifungal drug.

Both medications are used to reduce the growth of the fungus causing health symptoms or eliminate it outright. While they are vital to recovering from a serious Cryptococcus gattii infection, these drugs also come with several side effects and potential risks. It is important to discuss these risks with your doctor prior to taking the medication. You should also disclose any medications you are currently taking to avoid harmful drug interactions.

 
 
 

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