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Blastomycosis

The inhalation of fungal spores found in soil is what causes blastomycosis, a type of potentially serious lung infection. Not everyone exposed to this fungus, known as Blastomyces, develops symptoms like shortness of breath, cough, fever, and fatigue. When symptoms do occur, antifungal medications are an effective treatment.

How Does Antifungal Medication Work?

With blastomycosis, treatment depends on whether you experience mild/moderate or severe symptoms. A drug called itraconazole is typically used to treat less severe symptoms, while amphotericin B addresses more serious health effects:

 

Itraconazole

Oral itraconazole capsules are effective at treating fungal infections that involve the lungs. These medications reduce the growth of Blastomyces fungus, which can also ease symptoms. Patients typically take this medication for a period of three months. The side effects of itraconazole may include:

  • Abdominal pain
  • Heartburn
  • Constipation
  • Diarrhoea
  • Gas
  • Headache
  • Joint pain
  • Muscle pain/weakness

While all medications can cause unwanted effects, serious or lasting side effects should be reported to your doctor. Additionally, if you experience side effects like frequent urination, urinary incontinence, stomach pain, and ringing in the ear, seek immediate medical attention.

 

Amphotericin B

Amphotericin B is prescribed when doctors determine that a fungal infection could possibly be life-threatening. This medication works by binding to components within the fungus’ cell membrane, which allows the drug to destroy fungal cells. Amphotericin B is often administered intravenously for the maximum therapeutic effect. Side effects can include:

  • Fever
  • Chills
  • Headache
  • Abnormal heartbeat
  • Nausea
  • Muscle cramps

People on this medication should also avoid certain drugs due to potentially dangerous interactions, so be sure to provide your entire health history to your doctor when seeking treatment.

 
 
 

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