Bile plays an essential role in the digestive process, but certain health conditions can lead to dysfunction. Bile duct diseases, including cancer, gallstones, and cholangitis, obstruct the bile duct and stop the secretion from making its way to the small intestine.
Most bile duct diseases are treated via surgery. When it comes to cancer, a combination of surgery and radiation treatments can be used. As for symptoms of these diseases, many people complain of incessant itching, which is believed to result from bile accumulation in the skin. In this case, certain medications can be used to relieve itching and discomfort.
Known by the generic name cholestyramine, Questran is in a class of drugs known as bile acid sequestrants. These drugs work by stopping the bloodstream from absorbing bile in the stomach. They can also reduce bad cholesterol levels.
This medication can be used up to six times per day, although most people take it one to two times per day. It should be taken with two to six ounces of water.
While side effects can vary from patient to patient, the most common issues include:
Questran is also associated with more serious side effects that require immediate medical attention. These include:
Don’t hesitate to consult with your doctor if you experience a side effect that’s not listed here.
Certain medications can affect how Questran works. In addition to providing your doctor with a complete listing of medications you’re currently taking, including any vitamins or supplements, you should also avoid the following drugs:
Other medications may also cause unwanted interactions. Always talk to your doctor before starting a new prescription drug, vitamin, or herbal supplement.
Like Questran, Colestid (known by the generic name colestipol) is a bile acid sequestrant. This medication is also used to limit the effects of high cholesterol.
Children should not take Colestid, as the effects are not known at this time. When prescribed to adults, most people receive 2 to 16 grams per day. The drug can be administered in a single dose, or it can be broken into two separate doses. Every one to two months, doses will increase by two grams. Patients are encouraged to drink lots of water when taking the drug.
When it comes to side effects, gastrointestinal disturbances, such as constipation, gas, abdominal cramping, heartburn, and nausea, are among the most common. Doctors can increase the medication dosage gradually to avoid these effects. Less common side effects include:
Your doctor can provide more information on side effects and what you can expect when taking Colestid.
Colestid can bind to other oral medications, which may reduce their effectiveness. As a result, it’s recommended that people taking Colestid take other medications one hour prior to or four hours after taking the drug.
Propranolol, a beta blocker that treats heart issues, can be delayed when taken at the same time as Colestid. Accordingly, patients taking Propranolol must inform their doctors so their condition can be monitored while taking Colestid.