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Active Tuberculosis Infection

Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis. It affects the lungs when the bacterium is actively multiplying and causing symptoms.

Infections of tuberculosis began rising in 1980s, partly due to the conditions of HIV, the virus that causes AIDS. The virus affects the immune system, making it incapable of blocking TB pathogens.

In South Africa, more than 450,000 individuals develop TB active infection every year. Over the years, it has become one of the leading causes of death.

Symptoms

Typically, the symptoms of active tuberculosis (TB) can vary depending on the parts of the body that are affected, but some common symptoms include:

  • Persistent Cough: A cough lasting more than three weeks and producing phlegm or sometimes blood is a common symptom of active TB.
  • Chest Pain: Pain in the chest when breathing or coughing can be a symptom of lung TB.
  • Fatigue and Weakness: People with active TB may feel tired and weak and lose appetite and weight.
  • Fevers and Night Sweats: Active TB can cause fevers and chills, as well as excessive sweating, especially at night.
  • Shortness of breath: In severe cases of lung TB, you may experience shortness of breath.

Other symptoms: Active TB causes joint and muscle pain, abdominal pain, or swelling in the neck due to TB in the lymph nodes.

Causes

The bacterium called Mycobacterium tuberculosis is the main cause of TB. The infection typically spreads from person to person through the air when an infected person talks, coughs, or sneezes. The bacteria can remain in the air for many hours, allowing others to inhale and become infected.

Once inside the body, the bacteria can infect the lungs and cause active TB. However, only some people exposed to the bacteria will develop active TB. This is because the body’s immune system can often contain the infection and prevent it from spreading. In some people, especially those with weakened immune systems, the bacteria can multiply and cause active TB.

Risk Factors

The following are the risk factors that can lead you to develop TB symptoms.

  • Weak Immune System

People with weakened immune systems, such as those with HIV/AIDS, are at higher risk of developing active TB.

  • Recent TB Exposure

People recently exposed to someone with active TB are at higher risk of developing the infection.

  • Substance Abuse

Substance abuse, including alcohol and drug abuse, can weaken the immune system and increase the risk of developing active TB.

  • Malnutrition

Malnutrition, especially vitamin deficiencies, can weaken the immune system and increase the risk of developing active TB.

People with other medical conditions, such as diabetes and silicosis, are at higher risk of developing active TB.

Diagnosis or Complications

Diagnosis includes the following procedures:

  • Chest X-ray: A chest X-ray can show characteristic changes in the lungs that are typical of active TB.
  • Mucus Test: A sputum test involves collecting a sample of the mucus produced when coughing and examining it under a microscope for the presence of TB bacteria.
  • Skin Test: A skin test, also known as the tuberculin skin test (TST), involves injecting a small amount of protein from the TB bacteria into the skin. The test is positive if a raised, hard area forms at the injection site after 48 to 72 hours.
  • Blood Test: Blood tests can measure the body’s immune response to the TB bacteria, helping to confirm a diagnosis of active TB.

If not treated on time, active TB can cause serious complications such as:

Spread to other body parts: Active TB can spread from the lungs to other parts, including the lymph nodes, bones, and kidneys.

Scarring and Permanent Damage to the Lungs: Active TB can cause permanent scarring and damage to the lungs, leading to breathing problems.

Treatment & Prevention

The treatment of active tuberculosis (TB) typically involves a combination of antibiotics taken for six to nine months. The specific antibiotics used and the length of treatment will depend on the individual case. It may vary depending on the patient’s age, overall health, and disease severity.

To help prevent the spread of TB, it’s important to

  • Practice good hygiene: Cover nose and mouth when sneezing or coughing and keep your hands clean to help prevent the spread of the TB bacteria.
  • Avoid close contact with others: Stay away from others, especially those with weakened immune systems, until your healthcare provider says it’s safe to return to normal activities.
  • Get vaccinated: The BCG vaccine can help protect against TB, especially in children.

If you suspect you may have active TB, it’s important to seek medical attention as soon as possible for proper diagnosis and treatment. Early treatment and completion of the full course of antibiotics can lead to a full recovery from the infection.

 
 
 

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